Ok, I just read the JB4 install instructions. It does hook to the CAN wiring in the E-Box on the passenger side. With that being said you MUST remove those CAN wires. So, set your tune to MAP 0, remove the 2 CAN wires and hook up to the BMW system. This will work for sure I guarantee it.
2013 Alpine White F10 535i. JB4 S2, Quad Tip Magnaflow Exhaust, H&R Springs
2011 335ix Le Mans Blue w/ M Sport SOLD
2003 Turbo Cobra 765rwhp/650rwtq 9.77@126 pump gas, lifting @ the 1000ft mark