I've been running E85 blends (both 3 & 6 gallons blends in a full tank of 93). The most important thing is making sure you consistently stay within the fuel trims.
I'd recommend that you use Duralube products every so often, specifically their Flex Fuel Enhancer
and Direct Injection System Cleaner
Here's the website so you know what to look for (https://www.duralube.com/Products.aspx
), I was able to buy it in Walmart.