probably isn't going to hurt with regular maintenance.
Ideally there shouldn't be any fine particulate matter in your methanol, and if using RO/DI water ito cut the methanol should have 0 Total dissolved solids,
However the world is far from ideal. Running an additional filter that does 5-15 microns, will keep chunks of junk out of the combustion chamber. Over time this may impede methanol flow if not serviced.
2016 e63 amg s wagon matte white
2012 bmw m5 JB4+BCM