from woodland hills you get the benefit of the whole valley which means there's always lots to do and isn't too far of a drive to hollywood or glendale. or you can take a short drive in the other direction for the beach.
glendale is slightly more upbeat and alive, where you can actually see people walking on the streets all the time and there's cool cafe's and little markets and whatnot. Oh and its bmw and mercedez galore.
both are good choices. San Diego's cool too as long as your near somewhere like the gaslamp district. hope this helps