What kind of environment do you need the bag for? Are you looking to transport gear in a more urban setting (aka may want wheels?), in and out of cars / busses / cabs / airplane / subway, or are you thinking a more off-road environment, like trail hiking, skiing, etc?
I have a Lowepro Computrekker that I use when I travel, and it's a great bag for my laptop, an assortment of lenses, a couple bodies and a speedlight. However, it's not a very good "backpack", not something I'd want to hike with for 3 days. For that I use a LoweAlpine Contour IV, with a little padding to keep everything safe. Off the shoulder straps I like to hang a torso bag on the D rings, to hold a body with lens attached at the ready.
EDIT - to the OP, I just saw another post from you. Depending on how much gear you want to carry, I'd look into a daypack with a sleeve for your laptop. Most daypacks have lash points on the sides where you can attach a tripod or monopod with lash straps.
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1999 e46 328i Ti Silver / Black[retired]
2007 e90 335xi Jet Black / Black[retired]
2011 e70 X5 35d Vermillion Red / Cinnamon
2011 e92 M3 LeMans / Fox Red extended
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