IMO, they will be just fine. I've raced on tires with all kinds of crazy levels of treadwear, and I don't think you'll notice any difference with that chunk missing. I would be careful to inspect the rest of the tires for any other defects, however, especially any poorly installed patch jobs.
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2007 e90 335i in Montego Blue - Nov06 build
2012 X5 35d
2013 GTI
2002 Chevy 2500HD Duramax
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